الفهرس | Only 14 pages are availabe for public view |
Abstract Diabetes and impaired glucose tolerance re a cause of signi ficant morbidity and mortality. Impaired glucose metabolism is diagnosed at a fasting blood glucose of 2:1 l 0 and < I .:!6mg:d l (IFG) and postprandial blood sugar 2:1 40 and <200mg/d l (!GT). diabetes. Patients with impaired glucose tolerance may develop frank We studied whether there was detectable renal duplex ultrasonographic changes in patients with impaired glucose tolerance compared to a control group and if detectable renal vascular changes occur before the development of frank diabetes. We also examined the intima-med ia complex thickness of the common carotid artery in both groups. A statistically significant increase was found in the systolic velocity and relative index of the interlobar arteries between the two groups. No statistically significant increase was found in the intima- media complex thickness between the two groups. No fundal changes were detected i n either patient or control group. from this we concluded that the renal vascular changes could occur m patients with impaired glucose tolerance and this reflects that impaired glucose tolerance can lead to early vascular changes before patients develop frank di:::betes. Lack of significant results for the intima-media complex thickness can be explained by the fact that changes do not affect different segments in the vascular tree in a concordant manner. |