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Abstract Ultrasound irradiation has become a promising therapeutic tool in cancer treatment since ultrasound alone appears to selectively affect malignant cells without causing any deleterious effects to the surrounding normal tissues. While, the frequencies employed in medical applications are in the range between 500 kHz and 100 MHz, ultrasonic therapy frequencies are in the range between 0.15 and 3 MHz. Acoustic signals at these frequencies can be directed and coupled into body tissues where they propagate at the speed of sound. While tra\ eling through the various tissues, the sound waves undergo absorption, refracuon, reflection, and scattering, which depend on the acoustic properties of the issues (density, speed of sound, absorption coefficient, and homogeneity) and the changes in these properties at the tissue interfaces. The main objective of this thesis is to develop a numerical simulation of the interaction of therapeuttc ultrasound with a multi- tissue type system, and to develop an analytical model for calculating the temperature nse produced by ultrasound in these tissues. The Comsol software package employing the finite-element method (FEM) has been used to compute the radiated power density produced by a circular ultrasonic transducer disk. the heat deposition in each biological tissue and finally, the 2-8 temperature distribution during ultrasound hyperthermia process. Taken as a whole, this study provides a foundation for a better understanding of t1e interaction of ultrasound with biological tissues and the usage of focused ultrasound as a therapeutic tool. |