الفهرس | Only 14 pages are availabe for public view |
Abstract Staphylococcus aureus has been shown to be a potential pathogenic Gram-positive bacterium, causing a variety of diseases, such as skin and soft tissue infections, endovascular infections, pneumonia, endocarditis and septic shock. The development of methicillin resistance in S. aureus strains can be ascribed to production of a modified PBP2 (PBP2a) with low affinity to β–lactam antibiotics as a result of the acquisition of a mecA gene. Methicillin resistant Staphylococcus aureus (MRSA) constitute a major health care problem with a strong potential for dissemination and high rate of mortality and morbidity. Therefore, accurate and rapid identification of MRSA and their antimicrobial susceptibility profile are essential for treatment and prevention the spread of such strains. |