الفهرس | Only 14 pages are availabe for public view |
Abstract The high number of patients who go to the emergency room because of chest pain requires the availability of certain specific complementary tests that can help identify those patients who require hospital admission and, at the same time, are useful for the later categorization of the level of risk for those patients who present with acute coronary syndrome (ACS). These applications are important in terms of clinical significance, and are also important from the point of view of economic considerations. Heart rate variability (HRV) has a considerable potential to assess the role of autonomic nervous system (ANS) fluctuations in patients with various cardiovascular disorders. The aim of this study is to evaluate the diagnostic significance of heart rate variability indices detected by ambulatory ECG monitoring in patients diagnosed clinically as low risk acute coronary syndrome. The current study was conducted at Minia university hospital during period from May 2013 to May 2014. This study included 100 patients diagnosed clinically as low risk acute coronary syndrome (Non diagnostic ECG and negative cardiac enzymes). All patients in this study were subjected to: • Ambulatory ECG monitoring to obtain heart rate variability indices in the first day of admission. • Echocardiography to assess left ventricular Ejection Fraction, diastolic function. • Exercise Treadmill testing. • Invasive coronary angiography for patients with abnormal stress test to assess obstructive CAD This study demonstrated that Analysis of heart rate variability among patient suffering acute coronary syndrome is effective in predicting disease severity and screening of low risky population. Finally, we proved that reduced HRV indices in the acute stage are closely related to the presence of atherosclerotic CAD. |