الفهرس 
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Abstract
Domesticated Arabian camel, Camelus dromedarius, is the most important animal in the Arabian Desert, as it represents the main source of meat and its milk and urine are used for the maintenance of health and the treatment of various diseases.
PON1 is the best-studied member of a family of enzymes called serum paraoxonases, identified in vertebrates as well as in invertebrates. PONs exhibit a range of important activities, including drug metabolism and detoxification of organophosphates such as nerve agents. PON1 is synthesized in the liver, and then secreted into blood where it is mainly bound to HDL.
The aim of this study to investigate normal paraoxonase enzyme activity in the liver, heart and kidney of camels and other biochemical parameter at different ages.
This study carried out on a total of 32 male dromedary camels, classified into two groups.
group I:
This group contains 17 immature male camels ≤ 5 years old with ages ranged from (2.5-5 Y).
group II:
This group contains 15 mature male camels > 5years old with ages ranged from (6-9 Y).
Results of the present study revealed the following:
1- PON1, HDL and PON1/HDL ratio activity had no significant difference in mature and immature camels for serum and tissues. While, PON1 activity was highly significant increase in serum as compared to tissues. PON1 activity, HDL and PON1/HDL ratio was highly significant increase in liver than kidney and heart tissues.
2- A significant positive correlation between serum and liver paraoxonase enzyme activity.
3- There was significant increase in GPX value with increase age in liver but no significant difference in SOD, MDA levels between two groups, PON1 is positively correlated with GPx and SOD but negatively correlated with MDA.
4- A significant difference between the level of T.G and VLDL in the serum among two groups and no significant difference among two groups in other lipid profiles.
5- No significant difference among two groups in the level of hepatic T.G, total cholesterol and HDL. Liver contain high amount of T.G than total cholesterol and HDL.
6- PON1 was positively correlated with HDL ratio and negatively correlated with calcium and total cholesterol.
7- No significant difference in two groups in the Ca and phosphorus and level in serum and tissues.
8- Total protein in serum and liver tissue is within normal range within different two groups.