الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Skull base tumors represent a wide range of brain tumors and they can be approached through either traditional transcranial approaches or transsphenoidal approaches.
Microscopic transsphenoidal approach had been used for management of pituitary tumors, however midline lesions located anywhere from the cribriform plate to the midclivus can be approached through the extended endonasal transsphenoidal (EET) approaches.
Additional use of the endoscope with different angled lenses (0, 30, 45, 70), facilitates easier deal with the central skull base tumors through the extended endonasal transsphenoidal (EET) approaches.
This study was conducted on twenty patients presented with central skull base lesionsat different locations and with different extensions. Seven cases of craniopharyngiomas with suprasellar extension, five cases of anterior skull base meningiomas, two cases of neuroblastomas invading the anterior skull base from the nose, and six cases of clival chordomas with infrasellar and parasellar extension. Combined approach (transcranial and endoscopic transsphenoidal) was done in 2 cases of neuroblastomas.
Extent of tumor removal was (50% gross total, 45% subtotal more than 80% of the tumor, and 5% partial removal). As regard the post operative complications.