الفهرس 
Epidemiology of neuromuscular disorders
Limb-Girdle Muscular Dystrophy (LGMDOnly 14 pages are availabe for public view
 |  | from | 181 |  |  |
| | | from | 181 | | |
Abstract
Background and methods: Neuromuscular disorders (NMD) represent a heterogeneous group of disorders with variable severity. Since most neuromuscular diseases are hereditary and their proportions relative to each other vary according to gene frequency, which may differ between one region and another. Based on approximately twenty years of data collection from neuromuscular unit data records, faculty of medicine, Ain Shams University, we performed retrospective study to measure the frequency of different neuromuscular disorders, describe socio-demographic pattern and elucidate role of laboratory, histochemistry and immunostaining in different NMDs over the period 1997–2016. Results and conclusions: we found muscular dystrophies the most common NMDs (52.5%) especially limb girdle muscular dystrophy (26.2%) and Duchene muscular dystrophy (15.3%), high prevalence of male sex (64.3%), consanguinity (57.7%) and similar condition in family members (34.1%). Creatine kinase level was high in 76.56% of NMDs, also, histochemistry, immunostaining and genetic study help in diagnosis of disorders with clinical and phenotype similarities.