الفهرس 
ObesityOnly 14 pages are availabe for public view
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Abstract
Introduction: Obesity is strongly associated with coronary artery disease and known as an independent risk factor. So the aim of this study is to investigate the effects of cardiac rehabilitation program in obese and non- obese patients with coronary artery disease.
Materials and Methods: 60 patients with coronary artery disease participated in our study. At the beginning of study, body mass index, functional capacity, 12 leads surface ECG, lipid profiles and fasting blood sugar were evaluated and trans-thoracic echocardiography was done to assess left ventricular ejection fraction ,left ventricular end systolic and diastolic dimension. Then, these patients were divided into two groups, patients who had BMI ≥ 30 kg/ m2 were known as obese and who had BMI ˂ 30 kg/ m2 were known as non-obese group. All of them completed the period of cardiac rehabilitation program, and three months later all risk factors were examined for the second time in each group. Data were analyzed with SPSS software version 21. For comparing the mean of outcomes, independent t-tests and paired t-tests were used.
Results: In comparison between both group (obese versus no-obese) at baseline, our study found functional capacity was significantly higher in non-obese patients than in obese patients, and LDL level was significantly higher in obese patients, while there was no significant difference between both groups regarding total cholesterol, TG, HDL, FBS, LVEF, LVESD and LV end diastolic dimension. In obese group, our study found that there was significant improvement BMI, SBP, DBP, functional capacity, total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, FBS at the end of CRP but there was no significant change in LVEF, LVESD, and LVEDD. In non-obese group, our study found that there was a significant improvement in BMI, functional capacity, total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides, FBS, LVEF and LVESD at the end of CRP but there was no significant change in SBP, DBP and LVEDD.
Conclusion: our study found that involvement of patients in cardiac rehabilitation program improve their risk factors, functional capacity, lipid profile and echocardiographic parameters and hence cardiac rehabilitation program should be implemented in routine management of patients with coronary artery disease.