Search In this Thesis
   Search In this Thesis  
العنوان
Association between Serum Complement Anaphylatoxin C5a and Thrombotic Events in Patients Receiving Maintenance Hemodialysis /
المؤلف
Elsayed,Hithem Talaat
هيئة الاعداد
باحث / هيثم طلعت السيد احمد
مشرف / أسامـــــة محمــــود
مشرف / هيثـــم عزات عبد العزيز
تاريخ النشر
2016.
عدد الصفحات
131.p;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب الباطني
تاريخ الإجازة
1/10/2016
مكان الإجازة
جامعة عين شمس - كلية الطب - Internal Medicine
الفهرس
Only 14 pages are availabe for public view

from 132

from 132

Abstract

Background: End-stage renal disease (ESRD) is caused by several primary kidney and systemic disorders, which is manifested as renal failure. Thrombotic disorders are the most common complication in hemodialyzed ESRD patients is thrombosis of vascular access, which is a major cause of hemodialysis-associated morbidity. Aim: To find the association between complement components (C5a) and thrombosis in hemodialysis patients. Subjects: This study include (50) HD patients from hemodialysis unit in El Zaitoun specialized hospital. All patients receive hemodialysis sessions three times per week for four hours with bicarbonate solution & polysulfone dialysis membrane. The patient will be divided into two groups: group I: include 25 HD patients with thrombotic events e.g AVF thrombosis, DVT. group II: include 25 HD patients without any thrombotic events (control group). Results: The most prevalent etiology of ESRD in patients was HTN nephropathy (30%), unknown (30%) and obstructive uropathy 20%. The least prevalent etiology in patients was pyelonephritis, drug Toxicity, eclampsia, F.M.F and heavy metals toxicity, each represented 2%, while diabetic nephropathy was the cause for ESRD in 8% of patients and congenital anomaly 4%. All laboratory results have insignificant statistical difference between mean serum levels of urea, creatinine, and albumin, ESR, CRP and CBC in both groups (Pvalue˃0.05).