الفهرس 
REVIEW OF LITERATUREOnly 14 pages are availabe for public view
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Abstract
Some toxicological and pharmacological studies were carried out on Artemisia judaica; which is
commonly used in folk medicine in Egypt. LD5o of the ethanolic extract was 9.17 g!kg b.wt., while
the aqueous extract caused no mortalities in mice till 5 g!kg b.wt. in mice. Both extracts showed
significant anti-inflammatory and analgesic effects, but didn’t show antipyretic effect. The plant
extracts showed no significant effect on urine output and had no effect on the blood pressure or
pulse rate of normal rats. Moreover, the effect on blood glucose level was determined in nornial
and diabetic rats. The res.ults showed that the plant extracts had significant lowering effect on
the blood sugar level of diabetic animals, but had no effect on blood glucose of normal animals.
Both extracts showed significant hepatoprotective effect on the intoxicated liver using CCI4 in
rats. In addition; the ethanolic extract showed significant antioxidant activity in vitro, which
was more prominent than that of the aqueous extract. Prolonged administration of the plant
extracts for two months showed no adverse effect on blood picture, but there were slight changes in
the serum biochemical parameters, with observed decrease in body weight gain of the treated groups
when compared to control group. Th,e plant extracts showed inhibitory activity in the isolated
rabbit intestine, and the’ir action was simiiar to that of nicotine. They also showed varying
inhibitory effect on the uterine motility of rats at different stages of estrus cycle.