![]() | Only 14 pages are availabe for public view |
Abstract Likewise, the studies on the obstetric parameters associations and hematopoietic potential in umbilical cord blood are still few and showing conflicting results. This study may help reduce the costs, determine the best selection processes for donors of umbilical cord blood (to improve quality) and storage of umbilical cord blood units (to prevent storage of ineffective blood units), processing of umbilical cord blood units, optimize the collection procedure, and minimize the number of rejected umbilical cord blood units. The potential best umbilical cord blood units in conclusion can be identified and selected based on maternal and neonatal factors. This study showed that the maternal gravidity and neonatal gender are main factors examined to influence the umbilical cord blood volume, CD34+ cells count/viability, and TNC. The maternal age has no effect on the outcome variables. Maternal age data in our study suggests that it should not be a factor for selecting umbilical cord blood units. The neonatal order (first, second or third neonate) should be used to obtain optimal results. At the present time there are no records in the region, which concern about the optimal umbilical cord blood donors selection so we hope this research could help in future. In an ideal world UCB should be collected from every newborn at delivery with parental permission and stored in public banks. On reality, limited number of institutions has the fund to maintain such practice. UCB donation seems to be a very great option for many parents but it is not the case due to limited distribution of public banks and the high cost in case of private banks. Thus, it could be concluded that UCB banking opens a new era for SC therapy, as it diminishes to a great extent the problems facing SC transplantation especially finding a perfect match. So, UCB banking will pave the way for the scientists to exert much effort in achievement of humanity welfare and happiness through the new dream, Stem Cells. |