الفهرس 
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Abstract
The present study was designed to investigate some chemical composition of persimmon and also determine the effect of persimmon (whole, pulp, peel, methanol and water extract) on the nutritional and hyperlipidemic activity. This work was carried out on (48) adult albino male rats Sprague –Dawley strain weighting 128 ±5 g were classified into eight groups,(6 rats each) the first group rats were fed on basal diet only control negative(-ve) group and seven rat groups which injected (i.p) triton-X-100 (100mg/kg) to induce hyperlipidemic .and reclassified into non-treated control positive (+ve) group (fed on basal diet only), treated with (4.5 mg/kg b.w) of drug (atrovastatin), treated with(100mg/kg b.D) daily of holl, pulp, peel of persimmon dry ,treated with (5mg/kg b.w) daily of fresh persimmon methanol and water extract by stomach tube, for 60 days .The chemical composition of fresh and dry persimmon showed that the value of moisture content, T.carotoniod, B.carotenoid and Vitamin C of fresh persimmon were more than dry persimmon but the protein, fat, ash, carbohydrate, fiber, mineral, T. phenol, Flavoniods and Tannin in dry persimmon were higher than fresh persimmon .The results revealed that, the control (+ve) group showed a significant decrease in weight gain; feed efficiency ratio(FER), serum high density lipoprotein cholesterol (HDLc), T. protein, globulin, superoxide dismutase( SOD) and glutathione peroxidase (GSH) but a significant increase in serum cholesterol level, triglyceride , low density lipoprotein cholesterol (LDLc), very low density lipoprotein cholesterol (VLDLc), total lipid and phospholipids, amino transferees, (AST,ALT) and A/G compared with control (-ve) group at p 0.05. The holl, pulp, peel, methanol and water extract of persimmon rat group showed a significant increase in weight gain, (FER) serum, (HDLc), Total .protein , globulin, SOD and GSH. While showing a significant decrease in serum cholesterol, triglyceride, (LDLc), (VLDLc), total lipid and phospholipids, (AST, ALT) A/G and Malondialdehyde (MDA) at p 0.05 compared with control (-ve) group. The histopathological results showed that the whole, pulp, peel, methanol and water persimmon extract rat groups had lower changes. It can be concluded that, the administration of the whole, pulp, peel, methanol and water persimmon extract can lower the side effects of triton-x induced hyperlipidemic rats and reducing the risk factors for cardiovascular disease such as hyperlipidemia.