الفهرس 
Liver functionOnly 14 pages are availabe for public view
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Abstract
The current study was aimed to investigate the possible use of clover (Trifolium
alexandrinum) plant (flowers, leaves, stems, roots and seeds) on CCl4 - intoxicated rats.
For this purpose, the study included (35) rats (150±10 g) weight. Rats were fed on normal
(basal) diet. The animals were divided to 7 equal group, one was kept as control negative
(-ve) group, while the other 6 groups were injected by carbon tetrachloride in olive oil
50% v/v (3 ml/kg .B.wt) twice a week for 14 days to induce hepatotoxicity .
group (2) : Control positive (+ve), in which hepatotoxic rats Were injected by(CCl4)
and fed on basal diet for 28 days.
group (3): CCl4 hepatotoxicity rats were fed on basal diet containing 5% clover flowers
for 28 days.
group (4):CCl4 hepatotoxicity rats were fed on basal diet containing 5% clover leaves
for 28 days.
group (5): CCl4 hepatotoxicity rats were fed on basal diet containing 5% clover stems
for 28 days.
group (6): CCl4 hepatotoxicity rats were fed on basal diet containing 5% clover roots
for 28 days.
group (7): CCl4 hepatotoxicity rats were fed on basal diet containing 5% clover seeds
for 28 days.
At the end of the experimental (28 days), animal were scarified. Blood samples were
collected to determine the fullowing parameters : Blood glucose, lipids fraction of serum
(TC,TG, HDL-c, LDL-c, VLDL-c, AI), serum liver enzymes (AST, ALT, ALp,
AST/ALT ratio), serum protein fractions (total protein, albumin, globulin,
albumin/globulin ratio), serum bilirubin fractions (total bilirubin, direct bilirubin, indirect
bilirubin) , antioxidant enzymes (GPX , SOD, CAT) & kidney function (creatinine, urea,
uric acid). Liver, kidney, lungs, heart and spleen were kept on (10%) formalin solution
for histopathological examination.