الفهرس 
Liver CirrhosisOnly 14 pages are availabe for public view
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Abstract
Hepatic encephalopathy (HE), or portosystemic encephalopathy . represents a reversible decrease in neurologic function caused by liver disease. It occur most notably in patients with portal hypertension and shunting of blood away from the liver. In the setting of chronic liver disease, the onset of encephalopathy often is insidious and is characterized by subtle and sometimes intermittent changes in memory,personality, concentration, and reaction times.
In Egypt, although prevalence of liver cirrhosis secondary to chronic hepatitis C is high and one of the major health problems, studies evaluating the burden of cirrhosis and its complications are lacking. This study aims to evaluate the frequency and Prognosis of Hepatic Encephalopathy in Cirrhotic Patient with or without Hepatocellular Carcinoma among patients admitted to Ain Shams university Hospitals and factors affecting its occurrence and outcome.
Hepatic encephalopathy is associated with mortality rate of about 47.5% within 6 months . Because the disease adversely affects patients’ activities of daily living (eg, the ability to drive and work) and ability to care for themselves, it significantly decreases physical and mental quality of life.
There is a high mortality rate for HE patients who go into a coma. Recovery and risk vary from patient to patient and is dependent on the degree of liver failure, presence of other diseases, and time of treatment. It is important to appreciate that patients who have cirrhosis and have had episodes of HE are not allowed to drive or operate a motor vehicle, even if they may have “recovered” between episodes.
from our study it was concluded that there are different factors which play a key role in precipitating hepatic encephalopathy. Among these factors, infection, high protein intake, gastrointestinal bleeding, diuretic therapy, high protein intake are predominant. There is a definite need for health education and proper counseling in patients who were diagnosed as liver cirrhosis in relation to hepatic encephalopathy.
Early diagnosis and treatment of precipitating factor/s will reduce the mortality due to hepatic coma. Furthermore, this study will also open a new forum of discussion regarding demographical distribution of patient, knowledge and protocol regarding the medical workup of the patients with hepatic encephalopathy.