الفهرس 
Ischemic heart diseaseOnly 14 pages are availabe for public view
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Abstract
Coronary artery disease is a major health problem and a
major cause of mortality worldwide. In our study we aim to
uncover the relation between elevated HbA1clevel and
coronary artery disease and its severity in nondiabetics. One
hundred patients were enrolled in our study.We excluded any
patient with history of DM or met the criteria of diagnosis of
DM. We also excluded the patient who done previous coronary
revisualization which affect Gensini score. We also excluded
any factor affecting HbA1c level ashemoglobinopathies.
All the studied population was subjected to full history
taking, detailed clinical examination, 12 lead ECG, fasting
blood sugar and 2 hpp, HbA1c level, CBC, Complete lipid
profile ,echocardiography and diagnostic coronary angiography
with detailed interpretation of its result using Gensini scoring
system, we also divided the non- diabetics patient into two
groups, prediabetics group and non- diabetics group for better
evaluation.
Our study shows that there is highly significant relation
between HbA1c level and coronary artery disease in
nondiabetics. Our results shows also that as the HbA1c level
increases in non- diabetics the coronary arterypathology
calculated by gensini scoring system increases also until the patient enters the prediabetic category the risk becomes equal
and high independent at the level of HbA1c.
Our results raised the question about the role of HbA1c
as a separate predictor of CAD and if the current range of
diabetesshould be widened and treatment of diabetes should be
started earlier.