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العنوان
Clinical spectrum of post stroke seizures in a sample of egyptian patients/
المؤلف
Salama, Samy Yousry Eisa.
هيئة الاعداد
باحث / سامى يسرى عيسي سلامة
مناقش / أشرف مصطفى عبده
مشرف / حازم محمد معروف
مشرف / دعاء حنفى السلماوى
مشرف / ميرفت حامد المسدي
الموضوع
Neurology. Psychiatry.
تاريخ النشر
2017.
عدد الصفحات
58 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الأعصاب السريري
تاريخ الإجازة
2/3/2017
مكان الإجازة
جامعة الاسكندريه - كلية الطب - Neurology and Psychiatry
الفهرس
Only 14 pages are availabe for public view

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from 73

Abstract

Seizures are one of the most common complications of stroke. Overall, 5%–15% of stroke patients will experience a seizure within 2 years of stroke. The main risk factors for post stroke seizures include stroke subtype, location, and severity. Post stroke seizure rates are highest in those with intra parenchymal hemorrhage and large supra tentorial ischemic strokes, and lowest after transient ischemic attacks, lacunar infarcts, and brainstem strokes. Post stroke seizures are classified as “early” or “late” according to their temporal proximity to the stroke. Early seizures, also termed acute symptomatic seizures, occur within the first week following stroke. These early seizures are likely provoked by the metabolic and physiologic derangements associated with acute infarction or hemorrhage. Late seizures begin after a latent period of variable duration, usually weeks to years. Late seizures are thought to result from epileptogenesis, changes in neurons and networks that result in permanent hyperexcitability.
The aim of this current study was to:
• Determine the characteristics of post stroke seizures.
• Compare between early and late post stroke seizures.
• Correlate seizures with type of stroke.
This study was a retrospective study conducted on a 50 patients with post stroke seizures. Among the patients 26 were males and 24 patients were females with a total median age 57.5 year. All the patients were admitted to the neurology department of El- Hadara University Hospital.
All the patients included in this study were subjected to the followings:
• Complete history taking including: age, sex, onset of seizures either early (within one week) or late (after one week), type of seizures, frequency of seizures, status epilepticus and associated co- morbid conditions such as Hypertension, Diabetes mellitus, Ischemic heart disease and past history of stroke.
• Complete neurological examination.
• Complete laboratory investigations including: complete blood count (CBC), Blood Urea Nitrogen (BUN), creatinine level, liver enzymes (alanine aminotransferase and aspartate aminotransferase), Fasting blood glucose, lipid profile (Triglycerides-Cholesterol level) and serum electrolytes: sodium, calcium and potassium.
• Brain imaging: computed tomography (CT) for all cases and magnetic resonance imaging (MRI) if indicated.
• Inter ictal 16-channel electroencephalogram (EEG) using the international 10-20 EEG system. A 20-minutes artifact-free EEG was recorded using a Nihon Kohden electroencephalograph (Neuro fax EEG, Japan).