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العنوان
Impact of Donor’s Biliary Variant Anatomy on Adult Recipients of Living Donor Liver Transplantation\
الناشر
Yahia Ahmed Mortada Mahmoud Fayed ;
المؤلف
Fayed ; Yahia Ahmed Mortada Mahmoud
هيئة الاعداد
باحث / يحيي احمد مرتضي محمود فايد
مشرف / ابراهيم عبد القادر سلامه
مشرف / السيد احمد عبد الحفيظ سليمان
مشرف / اسلام اسماعيل ايوب
الموضوع
The Liver- Diseases.
تاريخ النشر
2016.
عدد الصفحات
167p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الكبد
تاريخ الإجازة
5/12/2017
مكان الإجازة
جامعة المنوفية - معهد الكبد - جراحة الكبد والقنوات المرارية
الفهرس
Only 14 pages are availabe for public view

from 95

from 95

Abstract

Summary
Living related liver transplant is an excellent treatment for patients with end stage liver disease.
Published reports suggest that 9–38% of patients after LDLT develop biliary complications. The reported complication rate does not seem to improve significantly with experience. Despite major advances in the field of liver transplant, biliary complications remain a major source of morbidity and mortality.
Today, post LDLT biliary complications are infrequent causes of death because they can be accurately and promptly diagnosed, and corrective measures are instituted before they become life threatening. The overall risk for mortality caused by biliary complications has been reduced to a small percentage of all patients who undergo liver grafting.
The aim of this work was to analyze the outcome of the variant biliary types in the donor and their impact on adult recipient’s outcome.
The records of a selected 107 patients in the adult age group who underwent LDLT in National Liver Institute, Menofiya University, until 31th December 2015 were retrospectively revised.
Those patients were 97 males (90.7%) and 10 females (9.3%) and their age ranged from 22 to 63 years old.
Biliary variations according to MRCP using (Varotti et al., 2004) classification into four types revealed Biliary variations in 27(25.2%) out of 107 cases 5 of them of type 2 14 of type 3a and 8 of type 3b.
There were statistically significant differences between recipients who had biliary complications and those who did not have, regarding type 1 with short stump.
There were statistically near significant differences between recipients who had biliary complications and those who did not have, regarding warm ischemia time.
Also these complications was associated with a statistically significant
Post-transplant hospital stay.
There were statistically no significant differences between recipients who had biliary complications and those who did not have regarding graft to recipient body weight ratio (GRWR), cold ischemia time (CIT), time of arterial anastamosis, type of biliary anastamosis, number of graft bile ducts, number of biliary anastamosis, and ABO blood group compatibility.
Biliary complications occurred in 53 out of the 107 recipients included in this study (49.5%). The complications included bile leak in 40 cases (37.5%), biliary strictures in 13 cases (12.1%) and concomitant biliary stricture and bile leak in 17 cases (15.9%).
Biliary complications contributed to the death of 11 recipients. They represent 10.2% of the total number of recipients and 25.58% of total number of mortalities.