الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 196 |  |  |
| | | from | 196 | | |
Abstract
Rapid restoration of infarct related arterial (IRA) flow is associated with improved ventricular performance and lower mortality among patients with myocardial infarction (Kaya et al., 2007). However, poor arterial flow and no-reflow phenomena may limit the benefits of recanalization of the IRA
Several biomarkers are associated with poorer outcomes in ST-elevation myocardial infarction (STEMI). Mean platelet volume (MPV) is an easily measured platelet indices, which increase during platelet activation Furthermore, increased MPV levels have been associated with poor clinical outcome in survivors of myocardial infarction and higher MPV correlates with thrombolysis failure in patients presenting with STEMI treated with thrombolytic therapy (Pereg et al., 2010). C-reactive protein (CRP) is an acute phase protein and several studies have shown that CRP may have prognostic value in patients with acute coronary syndromes and undergoing percutaneous coronary intervention (PCI) Uric acid, the end product of purine metabolism in circulation, is an independent risk factor for cardiovascular disease but the underlying pathophysiology is not clear. The relationship between circulatory uric acid levels and endothelial dysfunction has been demonstrated previously It has been shown that coronary flow reserve, a marker of coronary microvascular function, is significantly greater in participants with lower serum uric acid concentrations (Erdogan et al., 2006). It has been also demonstrated that high serum uric acid level is associated with slow coronary flow in patients underwent elective angiography.