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العنوان
Fetal middle cerebral artery/umbilical artery
pulsatility index ratio for Prediction of Neonatal
outcome among Women with Severe Preeclampsia /
المؤلف
Abbas, Luma Muaad.
هيئة الاعداد
باحث / Luma Muaad Abbas
مشرف / Ayman Abdul Razak Abou El Nour
مشرف / Mohamed El Mondooh Mohamed
مناقش / Ahmad Ali Al Anwar
تاريخ النشر
2017.
عدد الصفحات
124 P . :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
1/1/2017
مكان الإجازة
جامعة عين شمس - كلية الطب - امراض النساء
الفهرس
Only 14 pages are availabe for public view

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from 124

Abstract

In this study which included 100 women with severe preeclampsia admitted to Ain Shams Maternity University Hospital the aim was to evaluate the accuracy of middle cerebral/umbilical artery pulsatility index ratio in predicting admission to NICU, acidemia and low Apgar score at 5 minutes after birth in neonates of severe preeclamptic pregnant women.
There was a positive significant correlation between MCA/UA PI ratio <1 and higher rates of NICU admission, 5 minutes Apgar score <7, but there was no significant differences between women who had a MCA to UA PI <1 and umbilical artery PH <7.2.
The best cut off value of MCA/UA PI ratio for prediction of NICU admission was sensitivity 62.5%, specificity 71.43%, PPV 29.41%, NPP 90.91% and the accuracy 70%, the cut off value of MCA/UA PI ratio for prediction of low Apgar score at 5 min was sensitivity 50% and 88.10% specificity, estimated positive predictive value =44.44 and negative predictive value =90.24, and the cut off value of MCA/UA PI ratio for prediction of low UA PH was sensitivity 43.75%, specificity 69.05%, estimated positive predictive value =21.21, and negative predictive value =86.57.
MCA PI/UA PI ratio was found to be more sensitive and more specific in prediction of poor neonatal outcome in patients with severe preeclampsia specially in prediction of Apgar score at 5 minutes and incidence of NICU admission.
There was positive correlation between MCA/UA PI ratio and NICU admission as correlation coefficient = p value = 0.181, as Apgar score at 5 min there was poor correlation with p value =0.181 but there was negative correlation with umbilical cord PH with p value =0.547.
Considering that MCA PI / UA PI ratio reflects not only the circulatory insufficiency of the placenta by alteration in the umbilical pulsatility index, but also the adaptive changes resulting in modification of the middle cerebral pulsatility index, it seemed to be a potentially useful tool in predicting neonatal adverse outcome.
Doppler data combining both umbilical and cerebral velocimetery provide information on consequences of the placental abnormality; hence Doppler can be a useful tool in the management of patients with preeclampsia and can help in deciding the time of delivery so that the fetus can be saved.