الفهرس 
Epidemiology of HCCOnly 14 pages are availabe for public view
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Abstract
The study was conducted upon 90 subjects who were divided into three groups: group I included 40 patients with liver cirrhosis and hepatocellular carcinoma, group II included 30 patients with liver cirrhosis without HCC, group III had 20 healthy subjects as controls. group I was also divided into 2 subgroups, group Ia represents patients with AFP less than 200ng/ml and group Ib represents patients with AFP more than 200ng/ml.
In this study, the serum levels of Endoglin were highest in patients of group I with HCC compared to those with liver cirrhosis and the control groups with significant difference.
At a cut off value 220ng/ml, the diagnostic sensitivity and specificity of AFP for selective detection of HCC over the cirrhotic group was 67.5% and 100% respectively.
At a cut off value 1125pg/ml the diagnostic sensitivity and specificity of Endoglin for selective detection of HCC over the cirrhotic group was 90% and 76.67% respectively.
keywords
HCC , AFP , ENDOGLIN , CIRHOSIS, DIAGNOSTIC BIOMARKER , noninvasive biomarker