الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
 |  | from | 64 |  |  |
| | | from | 64 | | |
Abstract
The most common risk factors causing laryngeal carcinoma are tobacco and alcohol use with significant interaction between the two. Other observed risk factors include poor oral hygiene, GERD, and HPV infection, especially in nonsmokers. Most clinicians believe that nonsmoker patients with laryngeal carcinoma make up a distinct subset of cancer larynx patients perhaps with novel risk factors. The preceding differences suggest that non smokers with laryngeal carcinoma represent an etiologically and/or biologically distinct group of patients.
Although HPV has been studied as a possible risk factor for the development of cancer larynx, the role of HPV in non smoker patients with laryngeal carcinoma has not been determined. In this study we attempt to address this question by determining the prevalence of HPV DNA in laryngectomy specimens from both smoker and non smoker patients
In the present study, the population consisted of 68 patients with a histologically confirmed diagnosis of SCC of the larynx from July 2011 to June 2015.