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العنوان
Toxoplasmosis in relation to neurological morbidity
in children /
المؤلف
Kafhagy, Eman Ahmed Abbas.
هيئة الاعداد
باحث / إيمان أحمد عباس خفاجى
مشرف / أسامة أبو الفتوح الفقى
مشرف / نيفين توفيق عابد
مناقش / نجوى شعبان محمد على
الموضوع
Nerves, Periphera. Toxoplasmosis.
تاريخ النشر
2017.
عدد الصفحات
168 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2017
مكان الإجازة
جامعة بنها - كلية طب بشري - اطفال
الفهرس
Only 14 pages are availabe for public view

from 168

from 168

Abstract

Toxoplasmosis is caused by T. gondii protozoan and is estimated to
infect one-third of the world’s human population.
Children born with toxoplasmosis can be suffered from intellectual
disabilities, convulsions, spasticity, cerebral palsy, deafness particularly
in untreated children or those treated for a short period.
Cerebral Toxoplasmosis has been reported to cause seizures in
about 25% of infected cases by producing diffuse encephalitis or
localized lesions. Toxoplasma infection is implicated to have an
association with epilepsy either as a cause or a potential risk factor for its
occurrence.
Hearing impairment has been reported in about 20% of the
congenital toxoplasmosis cases.
The present study was carried out with a total of sixty cases, twenty
patients with cryptogenic epilepsy, twenty patients with nerve deafness
and twenty patients with cerebral palsy from those attending Benha
university hospital and Shebin El-Kom teaching hospital either inpatient
or outpatient clinic of pediatrics neurology and audio clinc and twenty
children sex & age matched with the patient groups served as control
group. The age group was between 1 year and 16 years old.
Each child included in this study was subjected to full history
taking, including main complain of the patient, socioeconomic status,
history of contact to animals. The demographic and life style
information was obtained through a survey questionnaire and clinical
examination according to the standard clinical sheet with special stress
on the neurologic examination.
Summary and Conclusion
- 122 -
The study results showed that no significant difference between the
studied groups regarding the socio-demographic characters but the
percentage of epileptic patients residing rural areas was higher than that
residing urban ones.
Also our results showed that there was statistically significant
increase in history of contact to animal in cryptogenic epilepsy group
comparing to control group (P= 0.025*) but there was no significant
increase in history of contact to animals among nerve deafness and CP
groups compared to control group.
As regard cooking preference there was statistically significant
increase in history of consuming well cooked meat in cerebral palsy
group comparing to control group (p= 0.047*) but there was no
significant among epilepsy and nerve deafness groups comparing to
control groups.
Our results revealed that there was no significant difference between
the studied groups regarding to consanguinity.
We found a statistically significant association between T. gondii
infection and cryptogenic epilepsy. The anti Toxoplasm IgG positive
cases represented 40% of the cryptogenic group, 10% of the control
group with (P = 0.028*).