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العنوان
Dyselxia: Neuro-anatomical approach using Diffusion Tensor Imaging Study/
المؤلف
Orabi,Ghada Tarek
هيئة الاعداد
باحث / غادة طارق عرابي
مشرف / صفاء رفعت الصادي
مشرف / ايهاب رجاء عبد الرؤوف
مشرف / خالد أبو الفتوح أحمد
مشرف / أحمد نبيل خطاب
تاريخ النشر
2017
عدد الصفحات
147.p:
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الطب (متفرقات)
تاريخ الإجازة
1/1/2017
مكان الإجازة
جامعة عين شمس - كلية الطب - phoniatrics
الفهرس
Only 14 pages are availabe for public view

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Abstract

Dyselxia: Neuro-anatomical approach using Diffusion Tensor Imaging Study
Safaa R. El-Sady *, Ehab R. Abdul-Raof**, Khaled Aboul-Fotoh***,
Ahmed N. Khattab**** GhadaOrabi*****
* Professor of Phoniatrics, Faculty of Medicine, Ain Shams University
** Professor of Clinical Genetics, National Research Centre
*** Professor of Radiology,Faculty of Medicine, Ain Shams University
**** Lecturer of Phoniatrics, Faculty of Medicine, Ain Shams University
*****Assistant Researcher of Phoniatrics, National Research Centre
Abstract:
Background: dyslexia is a specific learning disability affecting 15-20% of learning disabled children. Disruption of certain white matter tracts and regions have been linked to dyslexia, including the superior longitudinal fascicules and anterior corona radiata. Diffusion tensor imaging provides an important tool to investigate white matter changes along these areas.
Aim of the work: was to study white matter tract differences between dyslexic children and normal readers to establish a neuro-anatomical base for understanding dyslexia.
Subjects and methods: The current study included 20dyslexics and 20 normal control subjects, aged 4 to 9 years. All participants were subjected to diffusion tensor imaging as well as detailed protocol of assessment including full history, examination, and evaluation of reading skills and mental ability (IQ)
Results: There was a significant difference between dyslexics and controls in the fractional anisotropy of the anterior corona radiata. Reading abilities was correlated with right superior longitudinal fasciculus.
Conclusion: There is an association between the integrity of the white matter tract at the corona radiata area in the frontal lobe and between reading skills and the superior longitudinal fascicules a white matter tract that connects anterior with posterior language areas.
Keywords: dyslexia, diffusion tendor imaging , superior longitudinal fasciculus ,anterior corona radiata , dyslexia screening.