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العنوان
Role of neck dissections in patients undergoing salvage laryngectomy with a clinically and radiologically negative neck/
المؤلف
Abd Elaty,Ahmed Mohamed Kamel .
هيئة الاعداد
باحث / أحمد محمد كامل عبد العاطى
مشرف / هاني رياض محمد
مشرف / سامر أحمد إبراهيم
مشرف / وليد فرج عزت
مشرف / طارق عبد الحميد حمدى
تاريخ النشر
2017.
عدد الصفحات
177.p;
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الحنجرة
تاريخ الإجازة
1/7/2017
مكان الإجازة
جامعة عين شمس - كلية الطب - Otorhinolaryngology
الفهرس
Only 14 pages are availabe for public view

from 177

from 177

Abstract

Background: Routine ND for clinically and radiologically N0 neck in recurrent laryngeal SCC after previous RT or CRT remains debatable. Recorded incidence of occult nodal metastasis after STL plus ND in literature varies from 0% to 28.3%. The present study is to the best of our knowledge the first prospective analysis to date aiming at revealing the effect of performance of ND during salvage laryngectomy on regional recurrence, morbidity and survival.
Methods: A prospective chart review was achieved on 23 salvage laryngectomy patients who were clinically and radiologically N0 preoperatively. Performing ND and other factors were tested for associations with reginal recurrence, different postoperative complications, overall and disease free survival.
Results: Twelve patients underwent ND, from whom 2 had positive nodal pathology. ND was significantly associated increased overall complications with no significantly improved regional control and survival outcomes. Positive nodal pathology was associated with worst survival on multivariate analysis.
Conclusion: Outcomes advise to refrain from the imperative performance of neck dissection in all patients. END may be spared for late stages supra-glottic tumors and T4 glottic tumors.