![]() | Only 14 pages are availabe for public view |
Abstract Haematopoietic stem cell transplantation is now a corner stone in treatment of hematological disease, hepatic complications count for a significant part of morbidity and mortality during and after HSCT . We have shown that patients with mild liver dysfunction prior to BMT do not have an increased risk of post-transplant liver dysfunction. Patients who are HBs Ag positive or HCV antibody positive before BMT are also do not have an increased risk of post-transplant liver dysfunction. chronic GVHD and drug hepatotoxicity were major causes of liver dysfunction after BMT in our unit for allogenic BMT and drug hepatotoxicity for autologus BMT. Liver dysfunction can be determined in many cases with simple non– invasive tests used in conjuction with the clinical settings, specific treatment is then able to commenced in a majority of patients. |