الفهرس 
Carcinogenesis
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Abstract
Anticancer chemotherapy is a successful treatment of tumor to reduce the multiplying rate of tumor cells. Although the immunomodulatory effect of single chemotherapy has been investigated, the effects of combinatorial chemotherapy are not well defined. The aim of this study was to evaluate effects of the most common conventional anti-cancer chemotherapeutic drug: cisplatin (CIS), either individually or in combination with nicotinic acid on the tumor growth as well as on the total and differential numbers of leukocytes and genomic stability through its potential effect on PARP1.