الفهرس 
Assisted Reproductive Technology (ART)Only 14 pages are availabe for public view
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Abstract
Abstract
Background: Intracytoplasmic sperm injection (ICSI) is an in vitro fertilization procedure in which a single sperm is injected directly into an oocyte.Objective: Aim of the Work: The aim of the study is to determine the valueofAnti-Mullerianhormone (AMH), Inhibin-B and Antral follicle count as markers for ovarian responsein patients undergoing to Intra cytoplasmic sperm injection cycles. Methods:This observational prospective study was conducted at Ain Shams University Maternity Hospital, at ART (Assisted Reproductive Technique) unit on a sample of 100 women aged between 25 and 35 years, was enrolled for intracytoplasmic sperm injection (ICSI).Results:a good correlation between inhibin B and other numerical variables. There was strong positive correlation between inhibin B and AMH (rho, .727; p-value <.001) and strong negative correlation between inhibin B and both FSH (rho, -.674; p-value <.001) and LH (rho, -.608; p-value <.001) Inhibin B correlated moderately negatively with age (rho, -.449; p-value <.001) and moderately positively with AFC (rho, .407; p-value <.001), number of collected oocytes (rho, .444; p-value <.001) and number of sacs (rho, .514; p-value <.001). Inhibin B correlated positivelywith the number of fertilized oocytes (rho, .385; p-value <.001) and number of grade 1 embryos (rho, .355; p-value <.001). As regard pregnancy rate in the present study, the good-response group had significantly higher chemical and clinical pregnancy rates (76% versus 0%, p-value <.001 and 71% versus 0%, p-value <.001, respectively), as there was no chemical or clinical pregnancy had occurred in poorresponders Conclusion: AFC, AMH and Inhibin B are effective in predicting the ovarian reserve as well as the response to induction, and bothAMH and AFC are accurate for the assessment of ovarian reserve. Recommendations:A Larger scale studies including higher number of patients over longer periods of time are needed to verify the validity of this parameter as a marker of ovarian reserve in patients undergoing ICSI.