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العنوان
Protective Effect of Some Antioxidants (Vitamin E and Selenium) on Adverse Effects of Levofloxacin /
المؤلف
.Tohamy, Ahamed Abd El Fatah
هيئة الاعداد
باحث / احمد عبدالفتاح تهامى
مشرف / حسنى عبدالفضيل ابراهيم
مشرف / نجاح السيد عمر إدريس
مشرف / السـيد السـيد إمـام حسن
الموضوع
Vitamin E- pharmacology. Selenium. Pharmacology.
تاريخ النشر
2017.
عدد الصفحات
230 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
البيطري
تاريخ الإجازة
1/1/2017
مكان الإجازة
جامعة الزقازيق - كلية الطب البيطرى - الفارماكولوجيا
الفهرس
Only 14 pages are availabe for public view

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Abstract

The present study was designed to investigate the modulating effect of vitamin E (50mg/kg b.wt) and/or sodium selenite (1.5mg/kg b.wt) on adverse effect of levofloxacin (7.5 mg/kgm b.wt.) for 10 successive days.
This experiment was done on Eighty, four months old apparently healthy rats (Wistar strain) weighing between 150-200 gm average body weight, divided into 8 equal groups (10 rats in each).
group 1 Rats non treated (control).
group 2 Rats orally administrated with levofloxacin (7.5 mg/kg. b.wt) for 10 successive days
group 3 Rats orally administrated with Vitamin E (50mg/kg b.wt) for 10 successive days
group 4 Rats orally administrated with sodium selenite (1.5mg /kg. b.wt) for 10 successive days.
group 5 Rats orally administrated with Vitamin E and sodium selenite by same dose and period.
group 6 Rats orally administrated with levofloxacin and Vitamin E by same dose and period.
group 7 Rats orally administrated with levofloxacin and sodium selenite by same dose and period.
group 8 Rats orally administrated with levofloxacin, Vitamin E. and sodium selenite by same dose and period.