الفهرس 
H EMATOLOGICAL M ALIGNANCYOnly 14 pages are availabe for public view
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Abstract
As regarding the worldwide updates and re-evolution of chemotherapy, tumor management had been real and percentages of cure had become possible and remission percentages nowadays are going upward. Chemotherapy side effects appear to be more prominent and further interest in post-chemotherapy complications management is now a fact.
Chemotherapy induced cognitive impairment is one of the most prominent side effects as it negatively impact activities of daily living of the patients
Thus, many studies carried out to discuss this specific point revealing in total: some ideas about the main causes, how to diagnose, tests, correlations with other factors, predisposing factors, and management.
All these effort spent over years, but the actual mechanism is still unknown and we have only theories
At this study, we targeted our effort to find out a correlation between this cognitive insult with many factors like age, sex, type of malignancy, type of chemotherapy, duration of chemotherapy, route of its administration, and other comorbidity factors. To put our hands on some predisposing factors which give the way for how to avoid it.
Our study concludes that CICI is closely related to pre-medication comorbidities like diabetes, and hypertension. So prober control and management is necessary.
We found also, a strong correlation between CICI and the route of chemotherapy particularly those which are taken parenteral and crossing the blood brain barrier, which indicates more studies searching for better alternatives.
Another significant issue is the age and so we should consider low intensity chemotherapy with less neurotoxicity use in old patients.
Remission status gives less effect on cognition, so that malignancy control would give a better outcome as regards cognitive functions.