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Abstract BCC (or rodent ulcer) is the most common malignant cutaneous neoplasm found in humans.The tumor may occur at any age,but the incidence of BCC increases markedly after the age of 40. Although the reported risk factors for developing BCC include fair skin, tendency to freckles,degree of sun exposure, excessive sun-bed use, smoking,radiotherapy,phototherapy, male gender, and a genetic predisposition, cumulative lifetime sunlight exposure is a major risk factor for the development of BCC. Currently, there are numerous options available to treat BCCs including surgical,destructive,X-ray, intralesional chemotherapy, an topical therapies. Pulsed Dye Laser (PDL) is generally used to treat vascular skin lesions. BCCs are highly vascular tumors with clinically apparent telangiectasias. Although exact mechanism of action of using PDL to treat BCCs is unclear, the main hypothesis is antiangiogenic, via specific targeting of the numerous dilated blood vessels found in BCCs,PDL destroys the tumor’s blood supply leading to eventual demise of the tumor. It is believed that PDL therapy of BCCs offers a beneficial therapeutic modality because it is less invasive and destructive,quick,and simple,especially for patient with disabilities, multiple BCCs and coagulopathic disorders. |