الفهرس 
Physiology of LaborOnly 14 pages are availabe for public view
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Abstract
Background: Prostaglandins (PG F2 and PG E2) have long been involved in the spontaneous onset of labor. The normal process of labor appear to result in inflammation which result in increased prostaglandin synthesis, Prostaglandins produced in myometrial tissue contribute to the effectiveness of myometrial contractions during labor and may soften the cervix independent of uterine activity. Aim of the Work: The aim of this work is to assess the effect of intramuscular administration of dexamethasone on the progress and the duration of labor. Patients and Methods: This randomized, double-blind, controlled study was conducted in Ain Shams University Maternity Hospital. A total of 140 women undergoing induction of labor were included in this study after taking their consent for this clinical trial after full explanation of the trial. Results: Shorter duration from initiation of labor induction to beginning of active phase of labor than control group Dexamethasone group shows shorter duration of first stage of labor than control group. There was a high significant statistical difference between the two groups as regard first stage of labor of labor (p<0.001). Conclusion: The administration of 8 mg dexamethasone intramuscular during induction of labor is a simple applicable method to shorten the duration of labor. Recommendations: Further researches with more patients needed for the assessment of the effects of the corticosteroids on the duration of labor on the patients with unfavorable cervix. Further researches needed for the assessment of maternal and perinatal morbidity and mortality rate.