الفهرس 
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Abstract
This study aimed to investigate the effect of azolla caroliniana on hyperlipidemia and diabetic rats. Forty five white male albino rats, weighting 150 ± 10g, were used. The animals were divided into three main groups. The first main group (n=5) was kept as a control (-ve) group, while the second (n=20) fed on high fat diet for 21 day to induce hyperlipidemia. One of them was kept as control (+ve) group and the other three groups treated with different percentages of azolla algae (1%, 2.5% and 5%) from the basel diet , the third group (n=20) were injected by alloxan to induce diabetes. One of them was kept as a control (+) group and the other three groups treated with different percentages of azolla algae (1%, 2.5% and 5%) from the basel diet. At the end of the experimental period (28 days) rats were fasted over night before sacrificing and blood was collected then centrifuged to separate the serum to estimate serum glucose, liver functions (AST,ALT and ALP) kidney functions (urea, creatinine and uric acid) and lipid profile (TC, TG and HDL) while LDL and VLDL were calculated. Liver, kidney and heart removed from each rat, cleaned and weighted to estimate of organs weight. The obtained results revealed that, treatment groups by alloxan and high fat diet led to significant decrease in body weight gain (%) and increase in organs weights, serum glucose, cholesterol, triglycerides, LDL, VLDL, uric acid, urea nitrogen, creatinine, ALP, ALT, AST, and decreased HDL. Treating groups fed on azolla algae showed significantly (P≤ 0.05) decreased levels of serum glucose, AST, ALT, ALP, urea, creatinine, uric acid, improved serum lipid profile and other parameters including internal organs weights. The histopathological examination confirmed the paraments improvement. Key Words: Azolla caroliniana, Diabetic rats, Biochemical analysis, Hyperlipidemic rats, Glucose level.