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العنوان
Systematic Review of the Role of New ECG Changes in Predicting Major Cardiac Events after Non-Cardiac Surgeries/
المؤلف
Saad,Mohamed Khaled
هيئة الاعداد
باحث / محمد خالد سعد عبد اللطيف
مشرف / سامح ميشيل حكيم
مشرف / وائـــل رضـــا حســـين
مشرف / داليا محمود أحمد الفاوي
تاريخ النشر
2017
عدد الصفحات
59.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
التخدير و علاج الألم
تاريخ الإجازة
1/1/2017
مكان الإجازة
جامعة عين شمس - كلية الطب - Anesthesia
الفهرس
Only 14 pages are availabe for public view

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from 59

Abstract

Objectives: A systematic review was conducted to determine the role of new ECG changes in predicting major cardiac events (MACE) after non-cardiac surgeries.
Background: Patients undergoing non-cardiac surgery frequently experience major perioperative cardiac events. Perioperative myocardial ischemia is the single most important risk factor for major cardiac events after non-cardiac surgery. New ECG ST-segment changes suggestive of ischemia can predict these events.
Methods: We employed 2 search strategies (e.g., searching bibliographic databases), and we included all studies that assessed the role of new ECG changes suggestive of myocardial ischemia in predicting major cardiac events after non-cardiac surgeries. We calculated the odds ratio and the relative risk for each study to measure the association between new ECG changes and MACE after non-cardiac surgeries. We determined study eligibility and conducted data abstraction independently and in duplicate.
Results: Thirteen studies met eligibility criteria, and included a total of 5,467 patients among whom 456 experienced 1 or more major cardiac events after non-cardiac surgery. The average proportion of patients with new ECG ischemic changes was 31.2 %. In all of the studies the incidence of MACE was higher in patients with perioperative ECG ischemic changes compared to those who did not show ECG ischemic evidence. Odds ratio and relative risk showed statistically significant association between new ECG ischemic changes and MACE, except for 3 of the studies as they had too small sample size.
Conclusion: These results suggest that new ECG changes indicative of ischemia are strong predictors of major cardiac events after non-cardiac surgery.