الفهرس 
Introduction and Aim of the workOnly 14 pages are availabe for public view
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Abstract
Diabetes is a chronic disease and cardiovascular morbidity is very high among individuals with diabetes and atherosclerosis is a progressive change with its roots in childhood.
This study investigated the vascular intimal medial thickness changes of both common carotid arteries to show subclinical atherosclerosis using B-mode high resolution ultrasound.
Twenty-five children with type-1 diabetes aged 4 to 16 years (mean 11.3±SD 3.1) 13 females and 12 males were selected from out patient diabetes clinic, fulfilling the inclusion criteria designed for the study. Twenty apparently healthy children were selected as a control group; the 2 groups were matched for age, sex and BMI.
Patients and control were subjected to full clinical examination including blood pressure, BMI, and WHR and tested for lipid profile; HbA1c and microalbuminuria done for 10 diabetic patients only. Right and left CIMT were assessed by high resolution B-mode ultrasound.
In the present study, CIMT on both sides were significantly greater in type-1 diabetic children when compared to the healthy controls.
In addition, both CIMT showed a statistically significant positive correlation with age and duration of diabetes.
LCCA-IMT showed a statistically significant positive correlation with BMI, DBP, LDL, TG and HbA1c and negative correlation with HDL (protective).
RCCA-IMT showed a statistically significant positive correlation with daily insulin dose.