الفهرس 
Anatomy of the submandibular salivary gland in ratsOnly 14 pages are availabe for public view
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Abstract
Alendronate is a nitrogen containing bisphosphonate widely used in the
treatment of post-menopausal osteoporosis, corticosteroid-induced
osteoporosis, Paget’s disease as well as multiple myeloma. Its long term
administration could produce a wide variety of adverse effects among many
organs including the submandibular salivary glands.
Propolis is a natural resinous substance collected by honeybees from
buds and exudates of different plants. It has broad spectrum pharmacological
effects especially antioxidant and anti-inflammatory effects. So it is widely
used in the treatment of various conditions such as inflammations, microbial
infections, wounds, burns, sore throat, ulcers as well as diabetes, cardiac
diseases and even cancer.
This study was conducted to evaluate the effect of alendronate on the
histological structure of the submandibular salivary gland of adult male
albino rat and the possible protective effect of propolis using light
microscope, α-SMA immunohistochemistry stain and electron microscopy.
The present study was carried out on 40 adult male albino rats
weighing from 120 to 180 grams and were housed in suitable clean properly
ventilated cages under similar environmental conditions. They were divided
into two main groups:
(I) Control group:
It included 10 rats that were subdivided into two further subgroups (5
rats each).
Subgroup C1: included 5 rats kept without treatment.