الفهرس 
Introduction and aim of workOnly 14 pages are availabe for public view
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Abstract
This study had been carried out in El-minia university hospital during the period from February to December 2016 , 60patients undergoing general anesthesia with sevoflurane. enrolled and randomized into 3 equal groups comparing the effects of dexmeditomedine and magnesium sulphate in prevention of EA:
group C: received normal saline (10ml), 10 minutes before end of surgery(control group).
group D : received Dexmedetomidine (0.5 mcg/kg) diluted in normal saline10ml, 10 minutes before end of surgery..
group M : received Magnesium sulphate group received an intravenous dose of ( 30 mg/kg ) diluted in normal saline(30ml) before end of surgery divided in 3 syringes.
On arrival of the patient to operative room, standard monitors were applied to all children, which included, pulse oximety, NIBP, ECG.
General anesthesia was induced with sevoflurane 8% and 100 % oxygen via mask. Then, I.V cannula was inserted and atropine 0.01mg/kg was given. Oral tracheal intubation was performed by the aid of direct laryngoscopy, facilitated by using Atracium (0.5 mg /kg) (15 mg/kg) paracetamol( It is important to ensure that there is adequate analgesia, as pain behaviour can be misinterpreted as EA). Controlled ventilaion was instituted via Ayre’s T piece ,Ten minutes before the completion of the procedure, the study unknown drug were administered to the patients by the investigator .
The level of agitation was recorded using the AONO’S score for Emergence Agitation and PDEA score. Also the duration of recovery stay were recorded.
Our results showed that there was insignificant statistical difference between the three groups as regard the demographic data (age, sex and weight) and duration of surgery.
Also the results showed that dexmedetomidine effective as magnesium sulphate in reducing the incidence of emergence agitation.
In the contrast, magnesium sulphate is better than dexmedetomidine in the time to extubate and time to gain consciousness.
But, dexmedetomidine better hemodynamic stability than magnesium sulphate.