الفهرس | Only 14 pages are availabe for public view |
Abstract New onset of diabetes mellitus (NODAT) after renal transplantation is one of the common complications that is increasingly occurring among kidney transplanted recipients. The aim of this study is to assess the effect of immunosuppressive therapy on glycemic control after renal transplantation .The risk of (NODAT) or also called post-transplant diabetes mellitus (PTDM) increase with the time of transplantation .the incidence of NODAT ranges from approximately 2% to 25% with current immunosuppressive regimens, but rates as high as 46% were reported with earlier more diabetogenic regimens therefore early detection and prompt action are essential in reducing the risk of NODAT and its complications .Risk factors of PTDM are modifiable and unmodifiable risk factors ,unmodifiable includes age, ethinicity , hereditary and family history of diabetes, modifiable risk factor include obesity, immunosuppressive drugs ,transplant rejection, HCV and CMV infections. Consequences of NODAT include risk of cardiovascular disease , microvascular complications and reduced graft survival. |