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Abstract This study was conducted prospectively on 53 consecutive patients with ILDs in Chest department of Menoufia University during the period from January 2017 to October 2017. Patients were diagnosed ILDs and included in the study according to diagnostic algorithm of interstitial lung disease. The diagnosis of these cases was based on clinical features, serological tests (Anti-nuclear Ab, Anti-ds DNA, ESR, and RF), documented high-resolution CT scan findings and pulmonary function test results consistent with ILDs. Forty cases had idiopathic pulmonary fibrosis (based on exclusion of other known causes of ILDs and usual interstitial pneumonia pattern on HRCT in the form of basilar, sub pleural reticular opacities, and honeycombing with or without traction bronchiectasis). Thirteen cases had collagen vascular diseases related ILD (4 cases had sarcoidosis, 3 cases had rheumatic arthritis, 4cases had SLE, 2 cases had scleroderma). All patients admitted were subjected to transthoracic lung ultrasound for assessment of the presence of B-lines, the distance between them, assessment of pleura as regards pleural thickness, pleural surface (smooth, irregular or interrupted) and Presence or absence of lung sliding. These findings were compared with that of chest HRCT (ground glass, reticular, nodular or honey combing) and PFT as forced expiratory volume (FEV1), forced vital capacity (FVC), FEV1/FVC and partial arterial oxygen pressure. |