الفهرس 
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Abstract
Preterm birth (before 37 completed weeks of gestation) is a ‘major cause of postnatal death and a significant cause of long-term loss of human potential. There is a substantial long-term health impact from preterm birth due to increased risk both of death and of developing a wide range of chronic physical and neurological disabilities compared to full term births. Approximately 70% of neonatal deaths, 36% of infant deaths, and 25-50% of cases of long-term neurologic impairment in children can be attributed to preterm birth. The percentage of under-five deaths from preterm birth complications is still high in Egypt and our country is ranked as 144 worst on the list of 162 countries with prematurity related deaths comprising about 28.5% of all under-5 deaths in Egypt
Therefore, this study aims to compare the efficacy and safety of nifedipine and progesterone for maintenance tocolysis after arrested preterm labour and their perinatal outcome.
A prospective randomized comparative clinical study was conducted on 60 pregnant patient who suffered preterm labor, that divided into two groups: group I: consists of 30 pregnant patient who received nifedipine 20 mg tablets, and group: consists of 30 pregnant patient who received 400 mg of micronized progesterone vaginally at bed time.
All patients were attended from the Obstetrics and Gynecology outpatient clinic at Menoufia teaching hospital, Egypt, during the period from March to August 2017.
Efficacy was assessed based on cessation of uterine contractions after drug administration. While, spontaneously observed and reported side effects were recorded and evaluated. Drug tolerability as judged by the investigator was collected and analyzed. Side Effects were reported.