الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Depending on the fact that transcriptome (coding and noncoding RNAs) have been shown to be released from liver cells to the serum in a concentrated form inside exosomes. They may provide a novel class of noninvasive biomarkers for HCC diagnosis and prognosis as well as HCC therapeutic targets. We started our work to evaluate the efficiency of exosomal RAB11A-mRNA, miRNA-1262 and LncRNA-RP11513I15.6 as biomarkers for HCC patients and target these exosomal markers using pantoprazole in animal model
Serum exosomal RAB11A-mRNA, miRNA-1262 and LncRNA-RP11513I15.6 levels in serum sample could be potentially useful biomarkers for early diagnosis and prediction of progression of HCC patients. Pantoprazol could have therapeutic benefits for HCC patients