الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
The purpose of this study was to develop and characterize a novel
MgO ceramic coating for titanium alloy and evaluate the following:
1- Chemical and topographic characteristics of the coating
2- In-vitro Bioactivity after immersion in SBF.
3- In-Vivo Bone Osseointegration.
For the in-vitro study; a total number of 94 rectangular bar Grade V
(Ti6Al4V) specimens were used. The electrochemical deposition has been
utilized using Potentiostat for consistent voltage 1800 V for group I and 2400
V for group II for 30 min after insertion in 200 ml electrolyte (0.1M Mg
(NO3)2.6H2O) (pH=5.2). Sintering was done in a temperature controlled
furnace with temperature ranges from 300- 500ºc under vacuum.
Prepared samples were investigated for chemical compositional
analysis using X-Ray Diffraction (XRD) analysis and Fourier Transform
Infrared (FTIR) analysis followed by topographical analysis using Atomic
force microscope to investigate the coating roughness as well as the thickness.
For the In-vivo study; 9 implants were inserted in the tibia bone of
rabbits (3 implants for each group) and x-ray examination followed the
surgical procedure for 2 months. After sacrifice, histopathological evaluation
was done and histomorphometric analysis which showed the bone-to-implant
contact to confirm the osseointegration.
The In-Vitro study results; XRD and FTIR analysis showed and
confirmed the deposition of MgO coat with surface roughness considered a
mildly rough surface (400-500 μm) and the formed surface porosity in the
Nano and Macro size range.
For the In-Vivo study, all implants showed good osseointegration with
no difference between all the tested groups for bone density, cellular count,
Summary
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and Bone-to-implant contact ratio evaluation. Histopathological examination
showed the formation of new bone with active osteocyte at the coated
implants.