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Abstract Background: Both pulsed dye laser (PDL) and combined 585/1,064-nm (sequential dual-wave-length PDL and Nd:YAG) laser improves inflammatory skin disorders including acne vulgaris. Objective: To compare the efficacy of 585 nm pulsed dye laser versus its sequential combination with pulsed Nd:YAG laser 1064 nm (sequential dual-wave-length PDL and Nd:YAG) in the treatment of acne vulgaris. Patients and method: Thirty patients complaining of moderate or severe acne were treated with a single pass of PDL alone on half of the face and a single pass of combined 585/1064-nm laser on the other half for four treatment sessions at 2 weeks interval. Patients were followed up monthly for 3 months after the final treatment. They were assessed by the count and severity of the acne lesions & digital camera photographs. Results: The study showed that inflammatory acne lesions count was significantly reduced by 82.5% (p0.0001) on PDL-treated sides and by 83.5% (p0.00001) on combined 585/1,064-nm side 8 weeks after treatment start & 88.6% and 88.4%, respectively 12 weeks after treatment start, while reduction of non-inflammatory acne lesions was observed at 8 weeks by 58.4%, 71.5% respectively & after 12 weeks by 65.2%, 77.4% respectively. Although a difference was observed between the two treatment modalities on reduction of acne lesions, but it was not statistically significant. Grade of acne severity also showed significant reduction by both modalities. Results were sustained for a period of 3 months follow up. Conclusion: PDL and combined PDL / Nd:YAG nm laser treatment were found to be effective, safe & well tolerated treatment option for inflammatory and noninflammatory acne vulgaris. No statistically significant difference was observed between both treatment modalities. In addition, treatment results were sustained along the follow up period. |