الفهرس 
Introduction
HypertensionOnly 14 pages are availabe for public view
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Abstract
We enrolled patients with hypertension and a normal serum Cr level (<1.2 mg/dl). Liver function tests, total cholesterol,24hour urinary creatinine and serum Cr and CysC levels were measured on the same day for all patients.
90 patients with hypertension were enrolled in the study (64women and 26 men; age, 57.9±8.3years). All 90 patients were history of hypertension which are not on treatment or not complient on treatment.
Serum Cr and CysC levels were 0.8±0.2 and 1.44±0.37mg/L respectively.
the patients divided in to two groups: group I Which includes 65patients 46 females and 19 males, their ages ranges from ((37-74years) with a mean 57.9±8.3
This group has patients with history of hypertension with decrease creatinine clearance and has higher serum cyst level(0.85-1.89 mg/L) with a mean1.44±0.37.
group II Which includes 25 patients, 18 females and 7 males, their ages ranges from (35-69 years) with a mean 54.7±10.9, This group with history of hypertension with normal creatinine clearance and has lower serum cyst level(0.81-1.8mg/L) with a mean1.09±0.31.
In conclusion:
1-Serum creatinine (Cr) is not a reliable marker for early detection of renal dysfunction in in hypertensive patients.
2-Cystatin C (CysC) is more sensitive than Cr for detecting reduced renal function in these patients.
3- Serum CysC level was found to be a very useful marker for predicting the prognosis of nonazotemic patients with hypertension, because its detection of mild-to-moderate renal dysfunction in these patients was better rather than that based on the Cr level or a Cr-based assessment.