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العنوان
Fibroscan for Assessment of Non Alcoholic Fatty Liver Disease in
Type 2 Diabetic Patients in Tanta University Hospital /
المؤلف
Gamal El-Din, Mohammed Ibrahim Mohammed.
هيئة الاعداد
باحث / محمد ابراهيم محمد جمال الدين
مشرف / نصرت محمد عياد
مشرف / حنان حامد سليمان
مشرف / نهى السيد عشيبة
الموضوع
Internal Medicine.
تاريخ النشر
2018.
عدد الصفحات
134 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب الباطني
تاريخ الإجازة
21/2/2018
مكان الإجازة
جامعة طنطا - كلية الطب - Internal Medicine
الفهرس
Only 14 pages are availabe for public view

from 174

from 174

Abstract

Summary
Diabetes mellitus is one of the most common metabolic disorder
which affects multiple organs and systems.
NAFLD is a common complication of DM that may cause hazards
to the liver such as steatosis, steatohepatitis & fibrosis and may lead to
liver cirrhosis with long term disease.
Our comparative cross- sectional study aimed at using fibroscan
which is a non-invasive technique for assessment of liver steatosis &
fibrosis in diabetic patients.
For the purpose of the study 60 patients were included and they
were classified into 3 groups as following:
group (I): Included forty diabetic patients who were subdivided
into 2 subgroups: group IA with obesity and group IB without obesity.
group (II): Included twenty patients with obesity but without
diabetes as controls.
Patients and controls were subjected to the following
assessment:
 Thorough personal, present and family history taking
 Complete clinical examination: particularly for acanthosis
negricans, psychological disorders, neuropathy and
hypertension.
 Laboratory investigations including: FBG, 2 hours post
prandial blood glucose, lipid profile, liver function tests, blood
urea, serum creatininc, CBC, CRP and ESR. Pelvi –abdominal us.
 Fibroscan.
The following results were obtained:
 Steatosis was higher in diabetic patients when compared with
patients with obesity only (controls).
 Steatosis was higher in diabetic patients with central obesity
than diabetic patients without obesity.
 Fibrosis was higher in diabetic patients with obesity than
controls.
 Positive correlation in group IA between steatosis and serum
triglycerides.
 Positive correlation in group IA between fibrosis and the
following parameters: triglycerides, body mass index and fasting
blood glucose.
 Positive correlation in group IB between fibrosis and duration of
diabetes mellitus.