الفهرس 
SpondyloarthropathyOnly 14 pages are availabe for public view
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Abstract
Psoriasis (PsO) and psoriatic arthritis (PsA) are systemic inflammatory disorders with a complex etiopathogenesis that involve the interplay of environmental, genetic, and innate and adaptive immune system factors. PsO affects approximately 1-3% of the population usually during adulthood. Psoriatic arthritis (PsA) is a unique type of chronic inflammatory arthritis that occurs in association with the skin manifestations of psoriasis, commonly presenting with extra articular manifestations which includes nail involvement, enthesitis and, dactylitis and important comorbidities – especially cardiovascular morbidity, so the early diagnosis and treatment help prevent progressive joint involvement and disabilities.The prevalence of PsA among patients with PsO ranged between 6
and 40 % .The relationship between skin and joint manifestation is not clear.Although PsA can develop in 40% of psoriatic patients approximately 10 years after skin disease onset, the joint disease may precede the skin disease or both manifestations may develop in the same time.