الفهرس 
Possible sources of DDAC/BACOnly 14 pages are availabe for public view
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Abstract
Due to the fact that some agricultural products are an essential
nutritional food for infants as well as an important component of adult
nutrition, the contamination of theses commodities with residues of QACs
is a matter of serious concern.
These residues in food are often due to either environmental
contamination or via packaging procedures.
The Biocidal Products Directive (BPD) aims to establish a
single European market for biocides and to ensure that protection is
provided for users as well as for the public and the environment .
For these reasons, reliable analytical methods for the
determination of quaternary ammonium biocides are required for the
effective monitoring of occupational and environmental exposure as well
as in the quality control of manufactured products.
The use of a multi-residue method is the most efficient approach to
the analysis of QACs in Food in terms of analysis costs and turnaround
time.
Most of the described methods include more steps and high
consumption of various solvents and reagents.
The use of the QuEChERS method followed by LC-MS/MS found
to be the best combination for the determination of 5 QACs residues in
food because of high recovery, short time of analysis, low cost and safety.All of evaluated compounds showed a recovery ranging from 78 to
117% with relative standard deviations of less than 25% indicating
acceptable reproducibility.
The analytical method that was quick, easy, cheap, effective, rugged,
and safe (QuEChERS) for analysis of pesticide residues was used for
extraction of QACs in agricultural products (EN 15662:2008), in the
follow-up study.
In this study, a fast and easy method for determination 5 EU QACs
in Green Beans, Orange and Olive using LC-MS/MS for detection at the
0.01mg/kg limit of determination was developed.
The development included both optimization and detection
techniques.
The study also showed that the matrix effect of Green Beans,
Orange and Olive caused suppression during the detection of QACs
residues using LC-MS/MS and recommend calculating the matrix effect
to compensate the suppression.