الفهرس 
ST SEGMENT ELEVATION MYOCARDIAL
?Recommendations for Measurement of Serum Markers:Only 14 pages are availabe for public view
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Abstract
Summary
Atherosclerosis is a multi-factorial disease process that is influenced by
multiple pathophysiological factors. One of these factors is inflammation. Proinflammatory
mediators play an important role in the development of
atherosclerotic plaques. On the contrary, Anti-inflammatory mediators such as
HDL tend to protect the endothelial cells from the harmful effects of
inflammation.
The balance between pro-inflammatory and anti-inflammatory
mediators and its role in the development of atherosclerosis led to testing a
novel biomarker (MHR) that represent this balance.
The aim of this work was to study the relation between monocyte to
high-density lipoprotein cholesterol ratio and short term outcome in patients
with acute ST-segment elevation myocardial infarction undergoing primary
percutaneous coronary intervention.
The study was conducted on 100 patents, and the study sample was
divided into three tertiles according to MHR; Tertile 1 included 41 patients
with low MHR <10, tertile 2 with 36 patients having MHR of 10-20 and tertile
3 which included 23 patients with high MHR of >20.
Patients in each group were matched to other groups regarding different
demographic, clinical and laboratory parameters.
Patients in the high MHR tertile showed significantly lower systolic
blood pressure, higher Killip class II-IV, lower final angiographic TIMI flow,
higher WBCs, neutrophils and monocytes count, higher serum LDL level and
lower HDL levels and higher ejection fraction.