الفهرس | Only 14 pages are availabe for public view |
Abstract Background: Adipose tissue is now established as an active endocrine organ that has a big role in secretion of adipokines. Altered adipokine production and secretion can provide a link between adipose tissue dysfunction and obesity related disorders. as they are responsible for regulation of the whole body metabolism because they are involved in impaired insulin sensitivity or secretion, inflammation, fat distribution, satiety, and appetite, as well as endothelial dysfunction and atherosclerosis. Purpose: To study the relation between Fetuin A and NAFLD in patients with or without chronic hepatitis C viral infection in a group of Egyptian people. Patients and Methods: This study was conducted at the Gastroenterology and Hepatology unit, Department of Internal Medicine, Ain Shams University Hospital and Misr University for Science Technology Hospital. In the period from August 2017 to February 2018. Results: There was no statistically significant difference between control group and patient subgroups(NAFLD and HCV) regarding APRI and FIB4 score except fetuin A showed highly statistically significant increase in NAFLD group than control group and in Hepatitis C group than NAFLD and control group. Conclusion: There is an association between serum level of fetuin A and fatty liver in NAFLD and HCV which points to its possibility for being used as marker for prediction of NAFLD or even HCV and also predicting the future outcome for those patients. |