الفهرس 
Definition of chronic rhinosinusitisOnly 14 pages are availabe for public view
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Abstract
Summary
Chronic recurrent rhinosinusitis (CRS) is an inflammatory disease of the facial sinuses and nasal passages lasting longer than 12 weeks or occurring more than 4 times per year with symptoms usually lasting more than 20 days.
Immunoglobulin E (IgE) is one of five isotypes of human immunoglobulins, IgG, IgA, IgM, IgD, and IgE. IgE is synthesised by plasma cells.
IgE also has an essential role in type I hypersensitivity which manifests in various allergic diseases, such as allergic asthma, most types of sinusitis, allergic rhinitis, food allergies, and specific types of chronic urticaria and atopic dermatitis. IgE also plays a pivotal role in responses to allergens, such as: anaphylactic drugs, bee stings, and antigen preparations used in desensitization immunotherapy.
The present study was carried out to assay bacteriology of CRS and
to estimate total serum IgE level in the studied cases in relation to isolated micro organisms.
To fulfill our target, this study included 50 patients, 27 male (54.0%), 23(46.0%) female complaining of chronic rhinosinusitis (CRS) at the E.N.T surgical department, Tanta University Hospital, and 20 healthy persons without any nasal sinsses complaint as controls, they were 7 female (35 %) and 13 male (65%).
For all patients and controls the following was fulfilled: complete history taking, through clinical examination and from each subject nasal sinus swab was collected intraoperatively under endoscopic guidance and complete aseptic techniques and examined as follow: cultures on.