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العنوان
Hypoglossal-Facial Nerve Neurorrhaphy A Developing Modality To Repair Facial Nerve Injuries :
المؤلف
Elkhouly, Mohammed Saad Mohammed Abdullah.
هيئة الاعداد
باحث / محمد سعد محمد عبدالله الخولى
مشرف / خالد ابراهيم عبد العزيز بركات
مشرف / فاطمة فراج على
مناقش / وائل محمد عياد
مناقش / حامد محمد أحمد
الموضوع
Face - Wounds and injuries. Face - Surgery. Maxilla - Surgery. Surgery, Plastic. Maxillofacial Injuries - surgery.
تاريخ النشر
2018.
عدد الصفحات
113 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأسنان
تاريخ الإجازة
1/1/2018
مكان الإجازة
جامعة المنيا - كلية طب الأسنان - جراحة الفم والوجه والفكين
الفهرس
Only 14 pages are availabe for public view

from 132

from 132

Abstract

FN paralysis is a devastating condition that affects the patient’s quality of life and is considered a challenge for surgical repair. Peripheral FN injuries and transection is a common condition either for one or more branches of FN. Frontal and zygomatic branches which supplies orbital complex musculature concerned with great importance due to control of eye closure coordination.
The current study was conducted to solve the problem of acute facial nerve injuries repair. We choosed that novel method based on developing idea named supercharge concept as HFN to overcome the traditional surgical repair techniques drawbacks.
This study carried on 8 experimental animals (goats) as the (L) side left intact as a control side while the (R) side used as the working side. Under (TIVA), extended retromandibular approach done and exposure of HN performed, then longitudinal hypoglossal fascicle dissected and anastomosis with zygomatic nerve branch of facial nerve after iatrogenic cut and gap creation. The anastomosis pattern made in end to end fashion of hypoglossal fascicle which still attached to the HN trunk to the zygomatic branch of FN. End to side anastomosis of the proximal facial nerve with the lateral side of hypoglossal fascicle to achieve the supercharge concept . Slit incision at the lateral canthal area done to expose the OOMs fibers to be ready for electrophysiological evaluation device electrode.
Assessment scheduled for:
1-Clinical Assessment either Air flow test or Cotton bud touch test immediately preoperative, one month postoperative, three months post-operative and finally six months postoperative.
2-Electrophysiological Assessment either Contraction force of OOMs or duration till 50% fatigue of OOMs immediately preoperative, three months postoperative and finally six months postoperative .
Data collection and presentation statistically performed with GraphPad prism 7.0 software, calculating the mean and standard deviation and performing One way ANOVA test and Dependent Variable Tukey HSD.
The results of clinical assessment with the blinking score with the air flow test or with cotton bud touch reflex revealed that there is no significant difference between the immediate preoperative results and the six months postoperative.
The results of electrophysiological assessment regarding the force of contraction of OOMs in grams tension there is a high statistical significant difference between the immediate preoperative results and the six months postoperative. As the contraction force exceeded the control preoperative force and in some subjects it was doubled. The second observation with the time elapsed till 50% fatigue of the OOMs in seconds resulted in a high statistical significant difference between the immediate preoperative results and the six months postoperative. As the duration after six months was suboptimal and didn’t even equal the preoperative duration and in some subjects it was only the half.
Thus we reached a final opinion that the developing supercharge concept is reliable and valid and our HFN anastomosis is very helpful to restore the contraction force and function of the muscle, but we recommend further flow up period with larger sample size and maybe better electrophysiological assessment setup to observe possible fatigability reduction over the following few months.